Every Florida Book Project
The Society of S
Ethical Vampire Series #1
Susan Hubbard
2007
Ethical Vampire Series #3
Susan Hubbard
2010
The Year of Disappearances
Ethical Vampire Series #2
Susan Hubbard
2008
Annihilation
Southern Reach Series #1
Jeff VanderMeer
2014
Acceptance
Southern Reach Series #3
Jeff VanderMeer
2014
Authority
Southern Reach Series #2
Jeff VanderMeer
2014
The Coming
Joe Haldeman
Riding the Florida Time Line
Robert Lee Thompson
Down and Out in the Magic Kingdom
Cory Doctorow
Firefly
Breed
Owl Goingback
Burial Mound
Keith Edward Walker
Evenings on Dark Island
Rhett Devane & Larry Rock
The geography of Xanth, the setting of 42 novels by Piers Anthony, is based on Florida. So while not strictly set in Florida, these books have a strong Florida connection.
From Wikipedia:
"Geographically, modern Xanth resembles the state of Florida in the United States in shape, but has landmarks that mimic well known geographical features from around the world. One major example of this is the Gap Chasm, an enormous canyon a mile wide which completely bisects the country ... [like the] the Cross Florida Barge Canal, which, similar to the chasm, is generally forgotten except for those who stumble upon it. The Gap is guarded by a resident dragon, known as Stanley Steamer, and is crossed by means of treacherous bridges. Many of Xanth's other geographical features are puns on those of Florida (for example, Lake Ogre-Chobee and the Kiss-Mee River). The Florida Keys also exist, though they are, in Xanth, actual keys."